Synthesis, characterization, and in vitro SAR evaluation of N,N’-Bis(arylmethyl)-C(2)-alkyl substituted imidazolium salts

A series of C(2)-alkyl substituted N,N’-bis(arylmethyl) imidazolium salts were synthesized, characterized, and tested for their in vitro anti-cancer activity against multiple non-small cell lung cancer cell lines by our group and the National Cancer Institute’s-60 human tumor cell line screen to est...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: DeBord, Michael A., Wagers, Patrick O., Crabtree, Steven R., Tessier, Claire A., Panzner, Matthew J., Youngs, Wiley J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204360/
https://ncbi.nlm.nih.gov/pubmed/27939175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.11.075
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