The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells

Cancer cells exhibit multiple epigenetic changes with prominent local DNA hypermethylation and widespread hypomethylation affecting large chromosomal domains. Epigenome studies often disregard the study of repeat elements owing to technical complexity and their undefined role in genome regulation. W...

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Vydáno v:Genome Res
Hlavní autoři: Jordà, Mireia, Díez-Villanueva, Anna, Mallona, Izaskun, Martín, Berta, Lois, Sergi, Barrera, Víctor, Esteller, Manel, Vavouri, Tanya, Peinado, Miguel A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2017
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Method
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204336/
https://ncbi.nlm.nih.gov/pubmed/27999094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.207522.116
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