Quantification of Unmethylated Alu (QUAlu): a tool to assess global hypomethylation in routine clinical samples

Hypomethylation of DNA is a hallmark of cancer and its analysis as tumor biomarker has been proposed, but its determination in clinical settings is hampered by lack of standardized methodologies. Here, we present QUAlu (Quantification of Unmethylated Alu), a new technique to estimate the Percentage...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Buj, Raquel, Mallona, Izaskun, Díez-Villanueva, Anna, Barrera, Víctor, Mauricio, Dídac, Puig-Domingo, Manel, Reverter, Jordi L., Matias-Guiu, Xavier, Azuara, Daniel, Ramírez, Jose L., Alonso, Sergio, Rosell, Rafael, Capellà, Gabriel, Perucho, Manuel, Robledo, Mercedes, Peinado, Miguel A., Jordà, Mireia
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891138/
https://ncbi.nlm.nih.gov/pubmed/26859682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7233
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