Hematopoietic Stem Cell Mobilization Is Necessary but Not Sufficient for Tolerance in Islet Transplantation

Overcoming the immune response to establish durable immune tolerance in type 1 diabetes remains a substantial challenge. The ongoing effector immune response involves numerous immune cell types but is ultimately orchestrated and sustained by the hematopoietic stem cell (HSC) niche. We therefore hypo...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Stocks, Blair T., Thomas, Analise B., Elizer, Sydney K., Zhu, Yuantee, Marshall, Andrew F., Wilson, Christopher S., Moore, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2017
Assuntos:
Immunology and Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204317/
https://ncbi.nlm.nih.gov/pubmed/27797908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0444
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