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Hepatocytes Are the Principal Source of Circulating RBP4 in Mice
RBP4 is produced mainly by hepatocytes. In type 2 diabetes and obesity, circulating RBP4 is increased and may act systemically to cause insulin resistance and glucose intolerance. Observations that adipocyte RBP4 mRNA increases in parallel with circulating RBP4 in these conditions, whereas liver RBP...
Sparad:
| I publikationen: | Diabetes |
|---|---|
| Huvudupphovsmän: | , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Diabetes Association
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5204311/ https://ncbi.nlm.nih.gov/pubmed/27797907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0286 |
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