Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation.

Microtubule-associated protein 2 kinase (MAP kinase), which exists in several forms, is a protein serine/threonine kinase that participates in a growth factor-activated protein kinase cascade in which it activates a ribosomal protein S6 kinase (pp90rsk) while being regulated itself by a cytoplasmic...

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Detalhes bibliográficos
Main Authors: Seger, R, Ahn, N G, Boulton, T G, Yancopoulos, G D, Panayotatos, N, Radziejewska, E, Ericsson, L, Bratlien, R L, Cobb, M H, Krebs, E G
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC52038/
https://ncbi.nlm.nih.gov/pubmed/1712480
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