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Detection and Differentiation of Threonine- and Tyrosine-Monophosphorylated Forms of ERK1/2 by Capillary Isoelectric Focusing-Immunoassay

The extracellular signal regulated kinases ERK1/2 play important roles in the regulation of diverse cellular functions and have been implicated in several human diseases. In addition to the fully activated, diphosphorylated ERK1/2 protein, monophosphorylated forms of ERK1/2 have been observed, which...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kraus, Inga, Besong Agbo, Daniela, Otto, Markus, Wiltfang, Jens, Klafki, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522687/
https://ncbi.nlm.nih.gov/pubmed/26235103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12767
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