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Polymyxins facilitate entry into mammalian cells
Polymyxin B is an antibiotic used against multi-resistant Gram negative infections, despite observed nephrotoxicity. Here we report the synthesis of functionalized derivatives of polymyxin B and its per-guanidinylated derivative in order to further explore the structural requirements necessary to fa...
में बचाया:
| में प्रकाशित: | Chem Sci |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Royal Society of Chemistry
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5201209/ https://ncbi.nlm.nih.gov/pubmed/28044098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00488a |
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