Proportions of blood-borne Vδ1+ and Vδ2+ T-cells are associated with overall survival of melanoma patients treated with ipilimumab

Human γδ T-cells possess regulatory and cytotoxic capabilities, and could potentially influence the efficacy of immunotherapies. We analyzed the frequencies of peripheral γδ T-cells, including their most prominent subsets (Vδ1+ and Vδ2+ cells) and differentiation-states in 109 melanoma patients and...

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Pubblicato in:Eur J Cancer
Autori principali: Wistuba-Hamprecht, Kilian, Martens, Alexander, Haehnel, Karin, Foppen, Marnix Geukes, Yuan, Jianda, Postow, Michael A., Wong, Phillip, Romano, Emanuela, Khammari, Amir, Dreno, Brigitte, Capone, Mariaelena, Ascierto, Paolo A., Demuth, Ilja, Steinhagen-Thiessen, Elisabeth, Larbi, Anis, Schilling, Bastian, Schadendorf, Dirk, Wolchok, Jedd D., Blank, Christian, Pawelec, Graham, Garbe, Claus, Weide, Benjamin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201188/
https://ncbi.nlm.nih.gov/pubmed/27400322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2016.06.001
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