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A WD-Repeat Protein Stabilizes ORC Binding to Chromatin
Origin recognition complex (ORC) plays critical roles in the initiation of DNA replication and cell-cycle progression. In metazoans, ORC associates with origin DNA during G1 and with heterochromatin in postreplicated cells. However, what regulates the binding of ORC to chromatin is not understood. W...
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| Veröffentlicht in: | Mol Cell |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5201136/ https://ncbi.nlm.nih.gov/pubmed/20932478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.09.021 |
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