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Histone chaperone APLF regulates induction of pluripotency in murine fibroblasts
Induction of pluripotency in differentiated cells through the exogenous expression of the transcription factors Oct4, Sox2, Klf4 and cellular Myc involves reprogramming at the epigenetic level. Histones and their metabolism governed by histone chaperones constitute an important regulator of epigenet...
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| Veröffentlicht in: | J Cell Sci |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Ltd
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5201018/ https://ncbi.nlm.nih.gov/pubmed/27875275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.194035 |
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