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Histone chaperone APLF regulates induction of pluripotency in murine fibroblasts

Induction of pluripotency in differentiated cells through the exogenous expression of the transcription factors Oct4, Sox2, Klf4 and cellular Myc involves reprogramming at the epigenetic level. Histones and their metabolism governed by histone chaperones constitute an important regulator of epigenet...

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Podrobná bibliografie
Vydáno v:J Cell Sci
Hlavní autoři: Syed, Khaja Mohieddin, Joseph, Sunu, Mukherjee, Ananda, Majumder, Aditi, Teixeira, Jose M., Dutta, Debasree, Pillai, Madhavan Radhakrishna
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201018/
https://ncbi.nlm.nih.gov/pubmed/27875275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.194035
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