SIRT1 inhibits EV71 genome replication and RNA translation by interfering with the viral polymerase and 5′UTR RNA

Enterovirus 71 (EV71) possesses a single-stranded positive RNA genome that contains a single open reading frame (ORF) flanked by a 5′ untranslated region (5′UTR) and a polyadenylated 3′UTR. Here, we demonstrated that EV71 activates the production of silent mating type information regulation 2 homolo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Sci
Prif Awduron: Han, Yang, Wang, Lvyin, Cui, Jin, Song, Yu, Luo, Zhen, Chen, Junbo, Xiong, Ying, Zhang, Qi, Liu, Fang, Ho, Wenzhe, Liu, Yingle, Wu, Kailang, Wu, Jianguo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201017/
https://ncbi.nlm.nih.gov/pubmed/27875274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.193698
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