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Hyaluronic Acid Molecular Weight Determines Lung Clearance and Biodistribution after Instillation

Hyaluronic acid (HA) has emerged as a versatile polymer for drug delivery. Multiple commercial products utilize HA, it can be obtained in a variety of molecular weights, and it offers chemical handles for cross-linkers, drugs, or imaging agents. Previous studies have investigated multiple administra...

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Publicado en:Mol Pharm
Main Authors: Kuehl, Christopher, Zhang, Ti, Kaminskas, Lisa M., Porter, Christopher J. H., Davies, Neal M., Forrest, Laird, Berkland, Cory
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5200957/
https://ncbi.nlm.nih.gov/pubmed/27157508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.6b00069
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