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Polyarginine Molecular Weight Determines Transfection Efficiency of Calcium Condensed Complexes

Cell penetrating peptides (CPPs) have been extensively studied in polyelectrolyte complexes as a means to enhance the transfection efficiency of plasmid DNA (pDNA). Increasing the molecular weight of CPPs often enhances gene expression, but poses a risk of increased cytotoxicity and immunogenicity c...

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Autors principals: Alhakamy, Nabil A., Berkland, Cory J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207646/
https://ncbi.nlm.nih.gov/pubmed/23534410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp3007117
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