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AT2R Gene Delivered by Condensed Polylysine Complexes Attenuates Lewis Lung Carcinoma after Intravenous Injection or Intratracheal Spray

Transfection efficiency and toxicity concerns remain a challenge for gene therapy. Cell penetrating peptides (CPPs) have been broadly investigated to improve the transfection of genetic material (e.g., pDNA and siRNA). Here, a synthetic CPP (polylysine, K9 peptide) was complexed with angiotensin II...

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Dades bibliogràfiques
Publicat a:Mol Cancer Ther
Autors principals: Alhakamy, Nabil A., Ishiguro, Susumu, Uppalapati, Deepthi, Berkland, Cory J., Tamura, Masaaki
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707093/
https://ncbi.nlm.nih.gov/pubmed/26637367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0448
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