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Polyarginine Molecular Weight Determines Transfection Efficiency of Calcium Condensed Complexes
Cell penetrating peptides (CPPs) have been extensively studied in polyelectrolyte complexes as a means to enhance the transfection efficiency of plasmid DNA (pDNA). Increasing the molecular weight of CPPs often enhances gene expression, but poses a risk of increased cytotoxicity and immunogenicity c...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4207646/ https://ncbi.nlm.nih.gov/pubmed/23534410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp3007117 |
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