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Cu(I)-assisted Click Chemistry Strategy for Conjugation of Non-protected Cross-bridged Macrocyclic Chelators to Tumour-targeting Peptides

Copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry has inherent challenges for copper-labeled radiopharmaceuticals. An azide-modified phosphonate-based cross-bridged macrocyclic chelator was synthesized for click chemistry conjugation with azide-modified Y3-TATE (a somatostatin a...

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Detalhes bibliográficos
Publicado no:Dalton Trans
Main Authors: Cai, Zhengxin, Li, Barbara T. Y., Wong, Edward H., Weisman, Gary R., Anderson, Carolyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5200953/
https://ncbi.nlm.nih.gov/pubmed/25645688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4dt03897e
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