(64)Cu-Labeled Phosphonate Cross-Bridged Chelator Conjugates of c(RGDyK) for PET/CT Imaging of Osteolytic Bone Metastases

Objective: The goal of this research was to evaluate c(RGDyK) conjugated to phosphonate-based cross-bridged chelators using Cu-free click chemistry in the 4T1 mouse mammary tumor bone metastasis model in comparison with (64)Cu-CB-TE2A-c(RGDyK), which previously showed selective binding to integrin α...

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Vydáno v:Cancer Biother Radiopharm
Hlavní autoři: Ocak, Meltem, Beaino, Wissam, White, Alexander, Zeng, Dexing, Cai, Zhengxin, Anderson, Carolyn J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2018
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865263/
https://ncbi.nlm.nih.gov/pubmed/29634417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2017.2419
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