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Non-Cross-Bridged Tetraazamacrocyclic Chelator for Stable (64)Cu-Based Radiopharmaceuticals

[Image: see text] N-mono/dimethylated TE2A tetraazamacrocycles (MM-TE2A and DM-TE2A) were synthesized in high yields. Both Cu-MM/DM-TE2A complexes showed increased kinetic stability compared to that of Cu-TE2A, whereas Cu-DM-TE2A showed even higher in vitro stability than that of Cu-ECB-TE2A. MM-TE2...

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Detalhes bibliográficos
Main Authors: Dale, Ajit V., Pandya, Darpan N., Kim, Jung Young, Lee, Hochun, Ha, Yeong Su, Bhatt, Nikunj, Kim, Jonghee, Seo, Jeong Ju, Lee, Woonghee, Kim, Sung Hong, Yoon, Young-Ran, An, Gwang Il, Yoo, Jeongsoo
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027512/
https://ncbi.nlm.nih.gov/pubmed/24900586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400142s
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