Comparison of Conjugation Strategies of Cross-Bridged Macrocyclic Chelators with Cetuximab for Copper-64 Radiolabeling and PET Imaging of EGFR in Colorectal Tumor-Bearing Mice

[Image: see text] Epidermal growth-factor receptor (EGFR) is overexpressed in a wide variety of solid tumors and has served as a well-characterized target for cancer imaging and therapy. Cetuximab was the first mAb targeting EGFR approved by the FDA for the treatment of metastatic colorectal and hea...

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Bibliografiset tiedot
Julkaisussa:Mol Pharm
Päätekijät: Zeng, Dexing, Guo, Yunjun, White, Alexander G., Cai, Zhengxin, Modi, Jalpa, Ferdani, Riccardo, Anderson, Carolyn J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2014
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224567/
https://ncbi.nlm.nih.gov/pubmed/24720806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500004m
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