Synthesis and radiolabeling of chelator-RNA aptamer bioconjugates with copper-64 for targeted molecular imaging

Ribonucleic acid (RNA) aptamers with high affinity and specificity for cancer-specific cell-surface antigens are promising reagents for targeted molecular imaging of cancer using positron emission tomography (PET). For this application, aptamers must be conjugated to chelators capable of coordinatin...

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Bibliografiske detaljer
Main Authors: Rockey, William M., Huang, Ling, Kloepping, Kyle C., Baumhover, Nicholas J., Giangrande, Paloma H., Schultz, Michael K.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083585/
https://ncbi.nlm.nih.gov/pubmed/21658962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.05.010
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