Invariant chain targets HLA class II molecules to acidic endosomes containing internalized influenza virus.

The role of the HLA class II-associated invariant chain in the intracellular trafficking of HLA-DR molecules was examined in a transient expression system using HeLa cells. In the absence of alpha and beta polypeptides, invariant chain was retained in the endoplasmic reticulum (ER). In the absence o...

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Bibliographic Details
Main Authors: Lamb, C A, Yewdell, J W, Bennink, J R, Cresswell, P
Format: Artigo
Language:Inglês
Published: 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC52009/
https://ncbi.nlm.nih.gov/pubmed/2068076
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