Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules.

Lignende værker

• Invariant chain targets HLA class II molecules to acidic endosomes containing internalized influenza virus.
  af: Lamb, C A, et al.
  Udgivet: (1991)
• Stable surface expression of invariant chain prevents peptide presentation by HLA-DR.
  af: Roche, P A, et al.
  Udgivet: (1992)
• Invariant chain–MHC class II complexes: always odd and never invariant
  af: Cresswell, Peter, et al.
  Udgivet: (2014)
• Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain.
  af: Bijlmakers, M J, et al.
  Udgivet: (1994)
• In the absence of the invariant chain, HLA-DR molecules display a distinct array of peptides which is influenced by the presence or absence of HLA-DM
  af: Lightstone, Liz, et al.
  Udgivet: (1997)