Stoichiometry of HLA Class II-Invariant Chain Oligomers

BACKGROUND: The HLA gene complex encodes three class II isotypes, DR, DQ, and DP. HLA class II molecules are peptide receptors that present antigens for recognition by T lymphocytes. In antigen presenting cells, the assembly of matched α and β subunits to heterodimers is chaperoned by invariant chai...

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Main Authors: Koch, Norbert, Zacharias, Martin, König, Angelika, Temme, Sebastian, Neumann, Jürgen, Springer, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043101/
https://ncbi.nlm.nih.gov/pubmed/21364959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017257
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