A Novel Family of Human Leukocyte Antigen Class II Receptors May Have Its Origin in Archaic Human Species

HLA class II α and β chains form receptors for antigen presentation to CD4(+) T cells. Numerous pairings of class II α and β subunits from the wide range of haplotypes and isotypes may form, but most of these combinations, in particular those produced by isotype mixing, yielded mismatched dimers. It...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Temme, Sebastian, Zacharias, Martin, Neumann, Jürgen, Wohlfromm, Sebastian, König, Angelika, Temme, Nadine, Springer, Sebastian, Trowsdale, John, Koch, Norbert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2014
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887193/
https://ncbi.nlm.nih.gov/pubmed/24214983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.515767
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