A LGG-derived protein promotes IgA production through up-regulation of APRIL expression in intestinal epithelial cells

p40, a Lactobacillus rhamnosus GG (LGG)-derived protein, transactivates epidermal growth factor receptor (EGFR) in intestinal epithelial cells, leading to amelioration of intestinal injury and inflammation. To elucidate mechanisms by which p40 regulates mucosal immunity to prevent inflammation, this...

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Détails bibliographiques
Publié dans:Mucosal Immunol
Auteurs principaux: Wang, Yang, Liu, Liping, Moore, Daniel J, Shen, Xi, Peek, Richard M., Acra, Sari A, Li, Hui, Ren, Xiubao, Polk, D Brent, Yan, Fang
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199635/
https://ncbi.nlm.nih.gov/pubmed/27353252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.57
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