A LGG-derived protein promotes IgA production through up-regulation of APRIL expression in intestinal epithelial cells

p40, a Lactobacillus rhamnosus GG (LGG)-derived protein, transactivates epidermal growth factor receptor (EGFR) in intestinal epithelial cells, leading to amelioration of intestinal injury and inflammation. To elucidate mechanisms by which p40 regulates mucosal immunity to prevent inflammation, this...

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Bibliografiske detaljer
Udgivet i:Mucosal Immunol
Main Authors: Wang, Yang, Liu, Liping, Moore, Daniel J, Shen, Xi, Peek, Richard M., Acra, Sari A, Li, Hui, Ren, Xiubao, Polk, D Brent, Yan, Fang
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199635/
https://ncbi.nlm.nih.gov/pubmed/27353252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.57
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