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RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements
Receptor tyrosine kinases exhibit a variety of activation mechanisms despite highly homologous catalytic domains. Such diversity arises through coupling of extracellular ligand-binding portions with highly variable intracellular sequences flanking the tyrosine kinase domain and specific patterns of...
Gorde:
Argitaratua izan da: | Cell Rep |
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Egile Nagusiak: | , , , , , , , , , |
Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
Cell Press
2016
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5199340/ https://ncbi.nlm.nih.gov/pubmed/28009299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.061 |
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