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Regiodivergent and Diastereoselective CuH-Catalyzed Allylation of Imines from Terminal Allenes

A copper-catalyzed, chemoselective hydrometalation process enables the use of simple allenes as allylmetal nucleophile surrogates in imine allylation reactions. By modulation of the nitrogen-protecting group, either highly branched- or linear-selective addition can be achieved from the same allene....

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Liu, Richard Y., Yang, Yang, Buchwald, Stephen L.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198719/
https://ncbi.nlm.nih.gov/pubmed/27723269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201608446
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