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CuH-Catalyzed Enantioselective Alkylation of Indole Derivatives with Ligand-Controlled Regiodivergence

Enantioenriched molecules bearing indole-substituted stereocenters form a class of privileged compounds in biological, medicinal, and organic chemistry. Thus, the development of methods for asymmetric indole alkylation is highly valuable in organic synthesis. Traditionally, achieving N-selectivity i...

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Detalles Bibliográficos
Publicado en:J Am Chem Soc
Main Authors: Ye, Yuxuan, Kim, Seoung-Tae, Jeong, Jinhoon, Baik, Mu-Hyun, Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402987/
https://ncbi.nlm.nih.gov/pubmed/30696242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b11838
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