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RiboDiff: detecting changes of mRNA translation efficiency from ribosome footprints

MOTIVATION: Deep sequencing based ribosome footprint profiling can provide novel insights into the regulatory mechanisms of protein translation. However, the observed ribosome profile is fundamentally confounded by transcriptional activity. In order to decipher principles of translation regulation,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Bioinformatics
Päätekijät: Zhong, Yi, Karaletsos, Theofanis, Drewe, Philipp, Sreedharan, Vipin T, Kuo, David, Singh, Kamini, Wendel, Hans-Guido, Rätsch, Gunnar
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198522/
https://ncbi.nlm.nih.gov/pubmed/27634950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw585
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