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Gene- and pathway-based association tests for multiple traits with GWAS summary statistics

SUMMARY: To identify novel genetic variants associated with complex traits and to shed new insights on underlying biology, in addition to the most popular single SNP-single trait association analysis, it would be useful to explore multiple correlated (intermediate) traits at the gene- or pathway-lev...

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Detalles Bibliográficos
Publicado en:Bioinformatics
Main Authors: Kwak, Il-Youp, Pan, Wei
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198520/
https://ncbi.nlm.nih.gov/pubmed/27592708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw577
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