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Non-cell-autonomous Effects of Autophagy Inhibition in Tumor Cells Promote Growth of Drug-resistant Cells

Autophagy, the mechanism by which cells deliver material to the lysosome, has been associated with resistance to anticancer drugs, leading autophagy inhibition to be widely studied as a potential chemosensitization strategy for cancer cells. This strategy is based on the idea that inhibition of auto...

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Publicat a:Mol Pharmacol
Autors principals: Thorburn, Jacqueline, Staskiewicz, Leah, Goodall, Megan L., Dimberg, Lina, Frankel, Arthur E., Ford, Heide L., Thorburn, Andrew
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198514/
https://ncbi.nlm.nih.gov/pubmed/27974637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.106070
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