Caricamento...
Pharmacological profiling an abundantly expressed schistosome serotonergic GPCR identifies nuciferine as a potent antagonist
5-hydroxytryptamine (5-HT) is a key regulator of muscle contraction in parasitic flatworms. In Schistosoma mansoni, the myoexcitatory action of 5-HT is effected through activation of a serotonergic GPCR (Sm.5HTR(L)), prioritizing pharmacological characterization of this target for anthelmintic drug...
Salvato in:
| Pubblicato in: | Int J Parasitol Drugs Drug Resist |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2016
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5196489/ https://ncbi.nlm.nih.gov/pubmed/27397763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2016.06.001 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|