Genome instability in Alzheimer disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common form of dementia. Autosomal dominant, familial AD (fAD) is very rare and caused by mutations in amyloid precursor protein (APP), presenilin-1 (PSEN-1), and presenilin-2 (PSEN-2) genes. The pathogenesis of sporad...

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Bibliografiske detaljer
Udgivet i:Mech Ageing Dev
Main Authors: Hou, Yujun, Song, Hyundong, Croteau, Deborah L., Akbari, Mansour, Bohr, Vilhelm A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5195918/
https://ncbi.nlm.nih.gov/pubmed/27105872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2016.04.005
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