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Generation of a nested series of interstitial deletions in yeast artificial chromosomes carrying human DNA.

We have generated a nested series of interstitial deletions in a fragment of human X chromosome-derived DNA cloned into a yeast artificial chromosome (YAC) vector. A yeast strain carrying the YAC was transformed with a linear recombination substrate containing at one end a sequence that is uniquely...

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Detalhes bibliográficos
Main Authors: Campbell, C, Gulati, R, Nandi, A K, Floy, K, Hieter, P, Kucherlapati, R S
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51954/
https://ncbi.nlm.nih.gov/pubmed/2062854
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