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Generation of a nested series of interstitial deletions in yeast artificial chromosomes carrying human DNA.

We have generated a nested series of interstitial deletions in a fragment of human X chromosome-derived DNA cloned into a yeast artificial chromosome (YAC) vector. A yeast strain carrying the YAC was transformed with a linear recombination substrate containing at one end a sequence that is uniquely...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Campbell, C, Gulati, R, Nandi, A K, Floy, K, Hieter, P, Kucherlapati, R S
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51954/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2062854/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5744
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