Meiotic recombination and segregation of human-derived artificial chromosomes in Saccharomyces cerevisiae.

We have developed a system that utilizes human DNA-derived yeast artificial chromosomes (YACs) as marker chromosomes to study factors that contribute to the fidelity of meiotic chromosome transmission. Since aneuploidy for the YACs does not affect spore viability, different classes of meiotic misseg...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sears, D D, Hegemann, J H, Hieter, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49278/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1608938/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.12.5296
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