Global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae

In the yeast Saccharomyces cerevisiae, meiotic recombination is initiated by double-strand DNA breaks (DSBs). Meiotic DSBs occur at relatively high frequencies in some genomic regions (hotspots) and relatively low frequencies in others (coldspots). We used DNA microarrays to estimate variation in th...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gerton, Jennifer L., DeRisi, Joseph, Shroff, Robert, Lichten, Michael, Brown, Patrick O., Petes, Thomas D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17209/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027339/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.21.11383
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