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Global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae

In the yeast Saccharomyces cerevisiae, meiotic recombination is initiated by double-strand DNA breaks (DSBs). Meiotic DSBs occur at relatively high frequencies in some genomic regions (hotspots) and relatively low frequencies in others (coldspots). We used DNA microarrays to estimate variation in th...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Gerton, Jennifer L., DeRisi, Joseph, Shroff, Robert, Lichten, Michael, Brown, Patrick O., Petes, Thomas D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17209/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027339/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.21.11383
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