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CD4 peptide-protein conjugates, but not recombinant human CD4, bind to recombinant gp120 from the human immunodeficiency virus in the presence of serum from AIDS patients.

Sera from human immunodeficiency virus-positive (HIV+; Walter Reed stage 6) individuals inhibit the interaction between recombinant human CD4 and recombinant gp120 from HIV (rCD4 and rgp120, respectively), thereby interfering with the ability of soluble rCD4 to block infection with HIV or rCD4-toxin...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Ghetie, V, Slaughter, C, Wheeler, H T, Uhr, J W, Vitetta, E S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51943/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2062847/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5690
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