Normal serum immunoglobulins participate in the selection of peripheral B-cell repertoires.

In B-cell development, expression of immunoglobulin heavy-chain variable-region (VH) gene repertoires is determined by genetic mechanisms that favor rearrangement of the most D-proximal genes, resulting in overutilization of the VH7183 gene family early in ontogeny and in differentiating B cells of...

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Bibliographische Detailangaben
Hauptverfasser: Freitas, A A, Viale, A C, Sundblad, A, Heusser, C, Coutinho, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC51933/
https://ncbi.nlm.nih.gov/pubmed/1829525
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