Morphological and molecular features of astroblastoma, including BRAF(V600E) mutations, suggest an ontological relationship to other cortical-based gliomas of children and young adults

BACKGROUND. Astroblastomas (ABs) are rare glial tumors showing overlapping features with astrocytomas, ependymomas, and sometimes other glial neoplasms, and may be challenging to diagnose. METHODS. We examined clinical, histopathological, and molecular features in 28 archival formalin-fixed, paraffi...

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Gepubliceerd in:Neuro Oncol
Hoofdauteurs: Lehman, Norman L., Hattab, Eyas M., Mobley, Bret C., Usubalieva, Aisulu, Schniederjan, Matthew J., McLendon, Roger E., Paulus, Werner, Rushing, Elisabeth J., Georgescu, Maria-Magdalena, Couce, Marta, Dulai, Mohanpal S., Cohen, Mark L., Pierson, Christopher R., Raisanen, Jack M., Martin, Sarah E., Lehman, Trang D., Lipp, Eric S., Bonnin, Jose M., Al-Abbadi, Mousa A., Kenworthy, Kara, Zhao, Kevin, Mohamed, Nehad, Zhang, Guojuan, Zhao, Weiqiang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
Onderwerpen:
Basic and Translational Investigations
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193018/
https://ncbi.nlm.nih.gov/pubmed/27416954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now118
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