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Morphological and molecular features of astroblastoma, including BRAF(V600E) mutations, suggest an ontological relationship to other cortical-based gliomas of children and young adults

BACKGROUND. Astroblastomas (ABs) are rare glial tumors showing overlapping features with astrocytomas, ependymomas, and sometimes other glial neoplasms, and may be challenging to diagnose. METHODS. We examined clinical, histopathological, and molecular features in 28 archival formalin-fixed, paraffi...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Lehman, Norman L., Hattab, Eyas M., Mobley, Bret C., Usubalieva, Aisulu, Schniederjan, Matthew J., McLendon, Roger E., Paulus, Werner, Rushing, Elisabeth J., Georgescu, Maria-Magdalena, Couce, Marta, Dulai, Mohanpal S., Cohen, Mark L., Pierson, Christopher R., Raisanen, Jack M., Martin, Sarah E., Lehman, Trang D., Lipp, Eric S., Bonnin, Jose M., Al-Abbadi, Mousa A., Kenworthy, Kara, Zhao, Kevin, Mohamed, Nehad, Zhang, Guojuan, Zhao, Weiqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193018/
https://ncbi.nlm.nih.gov/pubmed/27416954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now118
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