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Deficiency in the Ubiquitin Conjugating Enzyme UBE2A in Alzheimer’s Disease (AD) is Linked to Deficits in a Natural Circular miRNA-7 Sponge (circRNA; ciRS-7)

Our understanding of the highly specialized functions for small non-coding single-stranded RNA (ssRNA) in the transcriptome of the human central nervous system (CNS) continues to evolve. Circular RNAs (circRNAs), a recently discovered class of ssRNA enriched in the brain and retina, are extremely st...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Zhao, Yuhai, Alexandrov, Peter N., Jaber, Vivian, Lukiw, Walter J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192492/
https://ncbi.nlm.nih.gov/pubmed/27929395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes7120116
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