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Biosynthesis of Circular RNA ciRS-7/CDR1as Is Mediated by Mammalian-wide Interspersed Repeats

Circular RNAs (circRNAs) are stable non-coding RNAs with a closed circular structure. One of the best studied circRNAs is ciRS-7 (CDR1as), which acts as a regulator of the microRNA miR-7; however, its biosynthetic pathway has remained an enigma. Here we delineate the biosynthetic pathway of ciRS-7....

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Vydáno v:iScience
Hlavní autoři: Yoshimoto, Rei, Rahimi, Karim, Hansen, Thomas B., Kjems, Jørgen, Mayeda, Akila
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371899/
https://ncbi.nlm.nih.gov/pubmed/32683316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101345
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