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Characterization of the Folding of a 5(2)-Knotted Protein Using Engineered Single-Tryptophan Variants
An increasing number of proteins that contain topological knots have been identified over the past two decades; however, their folding mechanisms are still not well understood. UCH-L1 has a 5(2)-knotted topology. Here, we constructed a series of variants that contain a single tryptophan at different...
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Publicado no: | Biophys J |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5192476/ https://ncbi.nlm.nih.gov/pubmed/28002735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.10.029 |
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