TAX1BP1 Restrains Virus-Induced Apoptosis by Facilitating Itch-Mediated Degradation of the Mitochondrial Adaptor MAVS

The host response to RNA virus infection consists of an intrinsic innate immune response and the induction of apoptosis as mechanisms to restrict viral replication. The mitochondrial adaptor molecule MAVS plays critical roles in coordinating both virus-induced type I interferon production and apopto...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Choi, Young Bong, Shembade, Noula, Parvatiyar, Kislay, Balachandran, Siddharth, Harhaj, Edward William
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192085/
https://ncbi.nlm.nih.gov/pubmed/27736772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00422-16
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