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TAX1BP1 Restrains Virus-Induced Apoptosis by Facilitating Itch-Mediated Degradation of the Mitochondrial Adaptor MAVS

The host response to RNA virus infection consists of an intrinsic innate immune response and the induction of apoptosis as mechanisms to restrict viral replication. The mitochondrial adaptor molecule MAVS plays critical roles in coordinating both virus-induced type I interferon production and apopto...

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Pubblicato in:Mol Cell Biol
Autori principali: Choi, Young Bong, Shembade, Noula, Parvatiyar, Kislay, Balachandran, Siddharth, Harhaj, Edward William
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192085/
https://ncbi.nlm.nih.gov/pubmed/27736772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00422-16
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